Homologous Recombination

High efficiency recombineering in lactic acid bacteria

Genetic Engineering / Biological Sciences / Vancomycin / Environmental Sciences / Mutation / Lactobacillus / Nucleic Acids / Phenotype / Anti-Bacterial Agents / Homologous Recombination / Lactococcus lactis / Lactobacillus / Nucleic Acids / Phenotype / Anti-Bacterial Agents / Homologous Recombination / Lactococcus lactis

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Modification of human β-globin locus PAC clones by homologous recombination in Escherichia coli

High Frequency / Escherichia coli / Nucleic Acids / Homologous Recombination / Genome sequence

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Modification of human beta-globin locus PAC clones by homologous recombination in Escherichia coli

Genetics / Biological Sciences / High Frequency / Environmental Sciences / Humans / Escherichia coli / Nucleic Acids / Plasmids / Molecular cloning / Genetic Recombination / Homologous Recombination / Genome sequence / Recombinant Protein / Recombinant Proteins / Genetic Markers / Escherichia coli / Nucleic Acids / Plasmids / Molecular cloning / Genetic Recombination / Homologous Recombination / Genome sequence / Recombinant Protein / Recombinant Proteins / Genetic Markers

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Generation of homoplasmic plastid transformants of a commercial cultivar of potato (Solanum tuberosum L.)

Plant Biology / Tobacco / Plant Science / Potato / Homologous Recombination / Solanum Tuberosum / Plasmid DNA / Particle Bombardment / DNA sequence / Solanum Tuberosum / Plasmid DNA / Particle Bombardment / DNA sequence

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Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency

DNA repair / Multidisciplinary / Sequence Analysis / Neural Development / Medulloblastoma / Mice / Animals / Genome Analysis / Spectrum / Genomic instability / Homologous Recombination / DNA binding proteins / Mice / Animals / Genome Analysis / Spectrum / Genomic instability / Homologous Recombination / DNA binding proteins

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AIF deficiency compromises oxidative phosphorylation

Membrane Proteins / Mitochondria / Apoptosis / Biological Sciences / Phylogeny / Brain / Humans / Glucose / Mice / Animals / Retina / Retinal Degeneration / Mitochondrial Respiratory Chain / Programmed cell death / Myocardium / Oxidative phosphorylation / Yeasts / Homologous Recombination / Lactic Acid / Adenosine Triphosphate / Brain / Humans / Glucose / Mice / Animals / Retina / Retinal Degeneration / Mitochondrial Respiratory Chain / Programmed cell death / Myocardium / Oxidative phosphorylation / Yeasts / Homologous Recombination / Lactic Acid / Adenosine Triphosphate

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Transgenic RNA interference in ES cell–derived embryos recapitulates a genetic null phenotype

Genetics / Stem Cells / Human Embryonic Stem Cells / RNA silencing / RNA polymerase / Multidisciplinary / Nature / Cell Division / Genetic Engineering / RNA interference / Cell line / Humans / Mice / Animals / Phenotype / Gene Function / Gene Targeting / Homologous Recombination / Embryos / ES cell / Multidisciplinary / Nature / Cell Division / Genetic Engineering / RNA interference / Cell line / Humans / Mice / Animals / Phenotype / Gene Function / Gene Targeting / Homologous Recombination / Embryos / ES cell

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Genetic and functional characterization of dpp genes encoding a dipeptide transport system in Lactococcus lactis

Genetics / Microbiology / Medical Microbiology / Intelligent Transport System / Gene expression / Substrate Specificity / Amino Acid Profile / Homologous Recombination / Amino Acid Sequence / Lactococcus lactis / Protein Transport / Substrate Specificity / Amino Acid Profile / Homologous Recombination / Amino Acid Sequence / Lactococcus lactis / Protein Transport

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Characterization of the Endogenous Plasmid from Pseudomonas alcaligenes NCIB 9867: DNA Sequence and Mechanism of Transfer

Genetics / Bacteriology / DNA replication / Horizontal Gene Transfer / Information Processing / Genetic Diversity / Biological Sciences / High Frequency / Mutation / Gene transfer techniques / Pseudomonas / Stability Analysis / Proteins / Pseudomonas putida / Plasmids / Transfer Function / Homologous Recombination / Base Sequence / Natural Transformation / DNA binding proteins / Genetic Markers / Plasmid DNA / DNA sequence / Genetic Diversity / Biological Sciences / High Frequency / Mutation / Gene transfer techniques / Pseudomonas / Stability Analysis / Proteins / Pseudomonas putida / Plasmids / Transfer Function / Homologous Recombination / Base Sequence / Natural Transformation / DNA binding proteins / Genetic Markers / Plasmid DNA / DNA sequence

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Modification of human β-globin locus PAC clones by homologous recombination in Escherichia coli

High Frequency / Escherichia coli / Nucleic Acids / Homologous Recombination / Genome sequence

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Modification of human beta-globin locus PAC clones by homologous recombination in Escherichia coli

Genetics / Biological Sciences / High Frequency / Environmental Sciences / Humans / Escherichia coli / Nucleic Acids / Plasmids / Molecular cloning / Genetic Recombination / Homologous Recombination / Genome sequence / Recombinant Protein / Recombinant Proteins / Genetic Markers / Escherichia coli / Nucleic Acids / Plasmids / Molecular cloning / Genetic Recombination / Homologous Recombination / Genome sequence / Recombinant Protein / Recombinant Proteins / Genetic Markers

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Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice

Stem Cells / DNA damage / DNA repair / Stem Cell / Multidisciplinary / Mitosis / Cell line / Mice / Animals / Bone marrow / PLoS one / Epithelial cells / Radiation Dose / DNA damage response / Gene Targeting / Chromosome segregation / Gastrointestinal Tract / Homologous Recombination / Human Fibroblasts / Cell Cycle Proteins / Cell Survival / Radiation Tolerance / Whole Body / Functional Status / Bone Marrow Cells / Mitomycin / Mitosis / Cell line / Mice / Animals / Bone marrow / PLoS one / Epithelial cells / Radiation Dose / DNA damage response / Gene Targeting / Chromosome segregation / Gastrointestinal Tract / Homologous Recombination / Human Fibroblasts / Cell Cycle Proteins / Cell Survival / Radiation Tolerance / Whole Body / Functional Status / Bone Marrow Cells / Mitomycin

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AIF deficiency compromises oxidative phosphorylation

Membrane Proteins / Mitochondria / Apoptosis / Biological Sciences / Phylogeny / Brain / Humans / Glucose / Mice / Animals / Retina / Retinal Degeneration / Mitochondrial Respiratory Chain / Programmed cell death / Myocardium / Oxidative phosphorylation / Yeasts / Homologous Recombination / Lactic Acid / Adenosine Triphosphate / Brain / Humans / Glucose / Mice / Animals / Retina / Retinal Degeneration / Mitochondrial Respiratory Chain / Programmed cell death / Myocardium / Oxidative phosphorylation / Yeasts / Homologous Recombination / Lactic Acid / Adenosine Triphosphate

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Expression of human poly (ADP-ribose) polymerase 1 in Saccharomyces cerevisiae: Effect on survival, homologous recombination and identification of genes involved in intracellular localization

Fluorescence Microscopy / Transcription Factors / Western blotting / Saccharomyces cerevisiae / Humans / Mutation / Nuclear pore complex / Histones / Cell nucleus / Fungal genome size / Homologous Recombination / Gene Expression Regulation / Mutation / Nuclear pore complex / Histones / Cell nucleus / Fungal genome size / Homologous Recombination / Gene Expression Regulation

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A two-step protocol for efficient deletion of genes in the filamentous ascomycete Podospora anserina

Genetics / Microbiology / Low Frequency / Mutagenesis / Escherichia coli / Genetic transformation / Aspergillus Nidulans / Homologous Recombination / Nucleic Acid / Genetic transformation / Aspergillus Nidulans / Homologous Recombination / Nucleic Acid

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Mouse Model for Human Arginase Deficiency

Cellular Biology / Gene Therapy / Biological Sciences / Molecular and cellular biology / Humans / Kidney / Liver / Mice / Female / Animals / Male / Nitrogen / Detoxification / Enzyme / Human Genome / Mouse Model / Mammary gland / Enzyme activity / Homologous Recombination / Quaternary Ammonium Compounds / Knockout Mice / Glutamic Acid / Growth Retardation / Kidney / Liver / Mice / Female / Animals / Male / Nitrogen / Detoxification / Enzyme / Human Genome / Mouse Model / Mammary gland / Enzyme activity / Homologous Recombination / Quaternary Ammonium Compounds / Knockout Mice / Glutamic Acid / Growth Retardation

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